Chikungunya
Chikungunya is a viral infection caused by the chikungunya virus (CHIKV), an alphavirus which is spread through mosquito bites. The mosquitoes that transmit chikungunya bite during the day, from sunrise to sunset, especially at dawn and dusk. They breed in natural and man-made containers (for example flowerpots and old tyres) and these are a risk factor for transmission if left around human habitation.
CHIKV was first isolated after an outbreak in Tanzania in the 1950s. It now occurs mainly in tropical and subtropical regions of the world but has also been found in parts of Europe and the USA. The mosquito that transmits CHIKV has spread very widely and has become a major global health problem.
Chikungunya is an unpleasant disease but is rarely fatal. Symptoms usually start about 4–8 days from a bite by an infected mosquito and include:
- sudden high fever
- severe joint pains (arthralgia) and muscle pains (myalgia)
- headaches
- sensitivity to light (photophobia)
- skin rashes
The symptoms usually improve within 1–2 weeks, but the joint pains can be severe and may persist for months or even years.
Occasional cases of eye, neurological and heart complications have been reported, as well as gastrointestinal complaints.
There is no specific antiviral treatment for chikungunya. Treatment consists of rest, fluids and medicines for pain and fever, such as ibuprofen or paracetamol.
Travellers visiting areas with on-going outbreaks are at risk of being infected with CHIKV. The risk areas are constantly changing and evolving, and travellers should check the latest information on our Country Information pages before they travel.
Prevention
Travellers should seek advice from a health professional prior to travel for information on the risk of chikungunya at their destination.
Mosquito bite avoidance is recommended, particularly during daytime hours.
Chikungunya vaccines
Two new vaccines have recently been approved for use in the UK.
IXCHIQ® is a live vaccine approved in the UK for individuals 18 years and older.* Vimkunya® is a virus like particle vaccine approved in the UK for individuals 12 years and older.
*See Joint Committee on Vaccination and Immunisation (JCVI) advice on age groups for the vaccine below
As of 9 June 2025, global data has highlighted 23 cases of serious adverse events in individuals 62 to 89 years of age who received IXCHIQ® during post marketing use. Two of the cases reported a fatal outcome. Many of the people affected also had other illnesses and the exact cause of these adverse events and their relationship with the vaccine have not yet been determined.
The UK government independent expert advisory body, the Commission on Human Medicines (CHM) has temporarily restricted the use of IXCHIQ® in people aged 65 years and over. This is a precautionary measure while the Medicines and Healthcare products Regulatory Agency (MHRA) conducts a safety review.
On 16 July 2025, JCVI published advice on the use of chikungunya vaccines in the UK. When vaccination is considered to be indicated, JCVI advises:
- Vimkunya® vaccine may be offered to individuals aged 12 years old and over
- IXCHIQ® vaccine may be offered to immunocompetent individuals aged 18 to 59 years old
Currently there is no evidence of a safety signal with the use of Vimkunya® in older adults. The JCVI did not consider it necessary to restrict the use of Vimkunya® at this time but note that this vaccine has not been used extensively. See JCVI news item (link above) for further details on indications for vaccination.
Table 1: chikungunya vaccines schedule and JCVI recommended age range
| Vaccine | Schedule | Length of protection | Age range |
| IXCHIQ® (live attenuated vaccine) Valneva |
Single 0.5ml dose given IM | The need for revaccination has not been established | 18–59 years* |
| Vimkunya® (non-replicating virus particle vaccine) Bavarian Nordic |
Single 0.8ml dose given IM | The need for revaccination has not been established | ≥12 years |
*See JCVI guidance regarding chikungunya vaccines, 16 July 2025
Resources
- More detailed information can be found in the Chikungunya factsheet
- European Centre for Disease Prevention and Control: Chikungunya worldwide overview
- UK Health Security Agency: Chikungunya
- World Health Organization: Chikungunya fact sheet
- Medicines and Healthcare products Regulatory Agency (MHRA). Chikungunya vaccine (IXCHIQ) temporarily paused in people aged 65 and over as a precautionary measure. 9 June 2025
- Joint Committee on Vaccination and Immunisation (JCVI) meeting minutes June 2025
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Recent News on Chikungunya
Chikungunya virus disease- Global situation report 2025
The World Health Organization have published a report on the current global situation of chikungunya virus disease (CHIKV)
Updated: 07 November 2025Chikungunya vaccination information
Chikungunya vaccinations authorised in the UK including updates on recent possible serious adverse events in older people and JCVI advice
Updated: 29 August 2025Changes to the Country Information pages: chikungunya vaccine recommendations
NaTHNaC has reviewed and updated the chikungunya country-specific information and vaccine recommendations
Updated: 29 July 2025Recent Chikungunya Outbreaks
Chikungunya in Hong Kong
As of 13 November 2025, a total of four confirmed locally acquired chikungunya cases have now been reported in Hong Kong for 2025. Please see our Topics in Brief article for further details on chikungunya.
Chikungunya in Italy
As of 4 November 2025, a total of 374 locally acquired chikungunya cases have been identified in four regions of Italy in 2025: Emilia-Romagna, Veneto, Tuscany, and Basilicata. The largest outbreak (316 confirmed cases) is located primarily in the province of Modena (Emilia-Romagna). Please see our Topics in Brief article for further details on chikungunya.
Chikungunya in Cuba
As of 24 October 2025, a total of 4,472 (with 120 confirmed) cases of chikungunya have been reported during 2025. Please see our Topics in Brief article for further details on chikungunya.
Chikungunya in Pakistan
As of September 2025, over 1,000 suspected cases of chikungunya have been reported in Pakistan during 2025. An increase in case numbers was noted between 4 May and 21 June 2025. Please see our Topics in Brief article for further details on chikungunya.
